TNL Car Title Loans provides car title loans for quick and easy access to fast cash. Call today to get your loan approved immediately. Portland is the largest and most populous city in the U.S. state of Oregon and the seat of Multnomah County. It is a major port in the Willamette Valley region of the Pacific Northwest, at the confluence of the Willamette and Columbia rivers. As of 2018, Portland had an estimated population of 653,115, making it the 25th most populated city in the United States, and the second-most populous in the Pacific Northwest (after Seattle). Approximately 2.4 million people live in the Portland metropolitan statistical area (MSA), making it the 25th most populous in the United States.